Grief generally is a little too straightforward or limited to use the application, which explains why Heart in the Oak or HOTO trumps it. It's more intended for a wider choice of classes, specifically those who use staves and maces, once they have to have at least four sockets.
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Heart from the Oak is extremely desirable for Paladins, Druids, Sorceresses, and Assassins due to the cast rate increase and mana steal per hit. It also gives some lovely skills that aid casters in their endeavors
For a physique armor rune word in which you can't make a mistake, Chains of Honor is probably the second-most prized. Another one of such all-around body armor buffs, Chains of Honor makes you tanky enough without sacrificing slots that might have been employed for offensive bonuses.
The 70 percent rise in defense has already been substantial, but Chains of Honor throws within a whopping +65 to resistances. You just can't venture to Hell without it. Making it more expensive as being a rune word is its Magic Find boost, as though all other benefits weren't enough already.
If you thought Grief was the most effective one-handed melee weapon, then you most definitely haven't gotten the opportunity to try out Dream. It's by far the most effective Auradin helmet/shield, in fact, it is somewhat viable for other melee builds. Its primary strength is based on the fact that you can place it both on shields and helmets, meaning you'll have two active Dream runewords available.
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This equals a level 30 Holy Shock Aura. When combined with the Paladin's Conviction Aura, you do not even have to do anything whatsoever; just walk about the map plus the enemies will die on the amped-up Holy Shock Aura. Of course, it costs two Jah runes, this is why the Auradin is known as a luxury build.
Two Ber runes may be demanding — that is why you shouldn't strive for this rune word if you won't have the enabler ones like Enigma or Call to Arms. It's also somewhat of a high-end rune word. But the pricing is well-justified simply because this rune word permits you to breeze with the game without worrying about enemy resistance.
The level 12 Conviction Aura makes certain that the most powerful lightning builds like the Lightning Sorceress or Lightning Javazon can farm unopposed. Your character will never be the one deploying it, naturally; you should give it to an Act 2 Mercenary whilst him nearby for optimum resistance shredding.
It probably won't look like much regarding damage, however, it's almost mandatory being an endgame rune word. Because Call to Arms is the most beneficial buff any class may have in the game. It's practically a Barbarian life and skill bonus shout, but the most beneficial defense in buy d2r runes is stacking numerous life and vitality anyway.
The skill bonus is merely a mere plus one to your skill trees, but even that's enough to deliver some substantial DPS boost to all or any builds. That's why this rune word is really as universal since the Enigma armor rune word orgasm is a lot less overpowered. If you do find yourself having trouble surviving in Hell difficulty, consider prioritizing this rune word and spamming the Barbarian shouts.
Last and positively not least, the infamous and utterly godlike rune word, Jah-Ith-Ber — or Enigma. For many players, rendering it a goal to have Enigma is unrealistic. It's also one of the most expensive with regard to trading. The defense boost is significant enough, but that is not where Enigma's value lies.
Enigma is most prized due to the +1 to Teleport skill, which gives any class a teleport. Put it on a character that will hit hard enough and you also turn them into an untouchable deity which makes quick work of Diablo and then any opponent in PVP. Hopefully, Diablo 2: Resurrected retains it.
