Currently, the simplest way to head approximately acquiring Sigil Powder is to Nightmare Sigils of any tier. This is the exact in-game description of Sigil Powder in Diablo four.
In order to get your first Nightmare Sigil, you need to Diablo 4 items head to The Whispering Tree after beating the primary story and World Tier three Capstone Dungeon in Diablo four. Here, you may take on duties to acquire Grim Favors. You want 10 to earn a random cache, which has a threat to incorporate a Nightmare Sigil. You want to preserve doing this till you acquire a Nightmare Sigil.
You can then use that Nightmare Sigil to enter a Nightmare Dungeon. Once within the dungeon, Nightmare Sigils will drop as loot from random enemies and you will also get hold of them as a reward for completing the dungeon itself. Then, you'll have sufficient Nightmare Sigils to begin salvaging them so one can receive Sigil Powder. You can then use the Sigil Powder to make better-tier Nightmare Sigils.
It’s extremely of a complex technique, as you want to salvage a Nightmare Sigil that allows you to obtain Sigil Powder, however you then use the Sigil Powder to craft Nightmare Sigils. Once you get into the drift of the endgame in Diablo 4, you'll begin to buy Diablo 4 items easily understand how the system works.